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EC number: 200-816-9 | CAS number: 74-86-2
The American Chemistry Council Acetylene Panel reviewed the material in December 2006. They recognised acetylene has been used for over 100 years as an anesthetic and industrial chemical, and few complications of using this gas have been reported, published epidemiological studies have failed to establish a link between use of acetylene and cancer. Waxweiler, 1981 found no evidence of any association with liver angiosarcoma in workers exposed to a number of materials. Acetylene exposure was not a risk factor in mortality from lung cancer in a case-referent study in which exposure to chemicals in an acetylene and phthalic anhydride plant accounted for one third of the total number of lung cancer deaths (Riboli et al., 1988). A pilot study on 454 men found no association between occupational exposure to acetylene and the development of cancer (Siemiatycki et al., 1982). A study of 370 workers involved in acetylene cylinder manufacture between 1935 -1975, reported excess mortality from lung cancer, and cancer of the stomach and pancreas. However, no association between exposure to acetylene and lung cancer was identified (Newhouse et al., 1988). Acetylene also was not listed as a risk factor for developing cancer in a study of 632 Danish male molders (Hansen, 1991). In two case-controlled studies, acetylene exposure was not identified as a risk factor for developing multiple myeloma (Morris et al., 1986; Williams et al., 1989). In 1980 Rohm and Haas reported the findings of a Texas plant, which utilizes acetylene and other chemicals to produce acrylate and methacrylate ester, the excess of total cancer deaths in those hired from 1958 to 1962, could not be correlated with job-related causes.
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