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EC number: 273-606-8 | CAS number: 68990-52-3
A total of 80 rats (40 males and 40 females) Sprague-Dawley rats,Crl CD® (SD)were allocated to four groups, three of which received the test item, Heptadecanoic Fatty Acid Methyl Ester (C16-C18) while the other group received the vehicle (corn oil) by oral route (gavage) once daily under a dosage volume of 5 mL/kg. Animals will be dosed for 2 weeks prior to pairing, during pairing, during gestation and until at least day 4 post-partum for females or until sacrifice for non pregnant females and until necropsy for males following 4 weeks of treatment.
The following dose-levels were used:
. Group 1 (10 males and 10 females): 0 mg/kg/day,
. Group 2 (10 males and 10 females):100mg/kg/day,
. Group 3 (10 males and 10 females):300mg/kg/day,
. Group 4 (10 males and 10 females):1000mg/kg/day.
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