Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 215-175-0 | CAS number: 1309-64-4
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The lowest valid value for toxicity to aquatic microorganisms is a NOEC of 2.55 mg Sb/L and an EC50 of 27 mg Sb/L for inhibition of nitrification (EPAS, 2005).
Key value for chemical safety assessment
Additional information
There is one study available providing reliable data for toxicity to aquatic microorganisms (EPAS, 2005).
In this study (EPAS, 2005) the effect of SbCl3on nitrification inhibition in activated sludge was assessed according to the ISO 9509 protocol (Water quality – Method for assessing the inhibition of nitrification of activated sludge micro-organisms by chemicals and waste waters). The protocol was slightly modified as the NH4-N concentration in the prescribed medium had an inhibitory effect on nitrification. The test was performed by aerating a nitrifying sludge in the presence and absence of Sb. The nominal Sb concentrations used ranged from 1.1 mg Sb/L to 1200 mg Sb/L. The protocol was modified by washing the sludge with tap water instead of demineralised water and medium because the proposed buffer was not sufficient to ensure a stable pH. By modifying the protocol this way, an activity in the sludge of 4.5 mg N/(g. h) could be calculated, which lies within the proposed interval of 2 to 6.5 mg N/(g. h). Each test solution was set up in duplicate. The flasks were incubated for 4 hours at a constant temperature and aerated in the dark. No inhibitory effects could be observed at a measured concentration of 2.55 mg Sb/L. Based on measured Sb concentrations an EC50 of 27 mg Sb/L was derived (confidence interval of 14-52 mg/L).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
