Registration Dossier

Ecotoxicological information

Long-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

In accordance with column 2 of REACH Annex IX, no long term toxicity testing is proposed (required in section 9.1.6) as the chemical safety assessment does not indicate a need to further investigate the effects on fish. All data available on calcium nitrate itself and on the other nitrates show a very low toxicity. In addtion, the substance does have a very high water solubility and its chemical properties do not indicate bioaccumulation. Therefore, the study is not considered necessary.

Key value for chemical safety assessment

Additional information

Although the endpoint is waived, there are reliable 30d growth rate and 32d embryo-larval tests available for the structural related substance sodium nitrate from Adelman (2009).

In the 30d growth rate test the NOEC for juvenile Topeka shiner was 268 mg/L (growth rate) and the NOEC for Fathead minnow was 58 mg/L (mortality).

In the 32d embryo-larval test, the NOEC to Fathead minnow was 157 mg/L based on growth rate (no effect on embryo survival).

These tests confirm the low toxicity of sodium nitrate.

The read-across rationale can be found in the document attached in the appropriate target records.