Registration Dossier

Ecotoxicological information

Endpoint summary

Currently viewing:

Administrative data

Description of key information

There are two studies available on the toxicity of o-xylene to terrestrial plants and one to microorganisms. Based on the very similar physical-chemical properties of the o-, m- and -p-xylene isomers, as well as the similarity of the results from the acute ecotoxicity studies, we believe that it is appropriate to read across from the data for o-xylene to the other xylene isomers. Furthermore, due to the technical challenges of testing volatile substances, a validated TLM-EqP modeling framework was used to derive terrestrial effect values. These data were considered reliable; however, these were not used in the PNEC derivation, since experimentally derived aquatic effect values exist. The hazard to soil organisms was assessed by applying the equilibrium partitioning method (EqP) to the experimentally derived aquatic effect concentrations.

The testing with terrestrial macroorganisms except arthropods is currently ongoing (study plan RRR18025), and the dossier will be updated to include the results of the testing once it is complete.

Additional information

There are two studies available on the toxicity of o-xylene to terrestrial plants and one to microorganisms. Based on the very similar physical-chemical properties of the o-, m- and -p-xylene isomers, as well as the similarity of the results from the acute ecotoxicity studies, we believe that it is appropriate to read across from the data for o-xylene to the other xylene isomers. Furthermore, due to the technical challenges of testing volatile substances, a validated TLM-EqP modeling framework was used to derive terrestrial effect values. These data were considered reliable; however, these were not used in the PNEC derivation, since experimentally derived aquatic effect values exist. The hazard to soil organisms was assessed by applying the equilibrium partitioning method (EqP) to the experimentally derived aquatic effect concentrations.

The testing with terrestrial macroorganisms except arthropods is currently ongoing (study plan RRR18025), and the dossier will be updated to include the results of the testing once it is complete.