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EC number: 265-084-5
CAS number: 64741-82-8
A complex combination of hydrocarbons from the distillation of the products from a thermal cracking process. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C10 through C22 and boiling in the range of approximately 160°C to 370°C (320°F to 698°F).
A sample of light
catalytically cracked distillate was tested for eye irritation potential
in groups of nine male New Zealand White rabbits. Treated and control
eyes from three rabbits were flushed with lukewarm water for one minute
starting 20 to 30 seconds after instillation while the treated eyes of 6
rabbits remained unrinsed. Eye irritation was quantified according to
the method of Draize at 1, 24, 48, and 72 hours and 7 days, and results
presented as the primary eye irritation score (total irritation score
for all animals divided by the number of animals in the group).
No pain response
(vocalisation) was elicited from any animal following instillation of
the test material. No corneal or iridal irritation was observed.
Blanching of conjunctivae was exhibited by one Group 1 animal at the
1-hour timepoint. Irritation resolved by 72 hours, and no systemic
toxicity was observed throughout the study period. Based on calculated
irritation scores (0/80 for corneal, 0/10 for iridial, and 0.44/20 for
conjunctival for both washed and unwashed eyes), the test material is
classified as not irritating to rabbit eyes.
This study received a
Klimisch score of 2 and is classified as reliable with restrictions
because it is an acceptable and a well documented study report.
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