Superphosphates

Exposure related observations in humans: other data

Administrative data

Endpoint:

exposure-related observations in humans: other data

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

other: No data

Data source

Reference

Reference Type:

publication

Title:

A retrospective cohort mortality study of a phosphate fertilizer production facility.

Author:

Stayner, L.T., Meinhardt, T., Lemen, R., Bayliss, D., Herrick. R., Reeve, G.R., Smith, A.B., and Halperin, W.

Year:

1985

Bibliographic source:

Arch. Environ. Health 40:133-138.

Materials and methods

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

Phosphate fertilizer

IUPAC Name:

Phosphate fertilizer

Results and discussion

Results:

Overall, no statistically significant elevations in cause-specific mortality were observed for the entire study population. However, when the analysis was stratified by duration of employment and length of follow-up, a statistically significant (P < .05) excess in lung cancer mortality was observed among workers with more than 10 years of employment and follow-up (standardized mortality ratio = 411). Because of the small number of deaths involved, and because of a prior knowledge of a lung cancer cluster at this plant, the authors (NIOSH) state that these findings should be viewed as suggestive, and that other investigations in plants with similar exposures are needed to clarify whether an occupationally related lung cancer excess truly exists.