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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Description of key information

One key study and one supporting study have been identified as having assessed the short-term toxicity to aquatic invertebrates. The key study followed a guideline similar to the OECD guideline 202 and the supporting study followed the German Industrial Standard DIN38412 part 11 guideline.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
3 485 mg/L

Additional information

The key study followed a guideline similar to OECD 202, the concentrations (nominal) used were 0 (control), 1120, 1500, 2000, 2700, 3600, 4700, 6300 and 8400 ppm. This study concluded that the 48 h LC50 of tetrahydrofuran to daphnia magna is 3485 ppm. The supporting study followed the DIN38412 part 11 guideline but was conducted over a 24 hour exposure period and did not reveal the range of concentrations used. This study concluded that the 24 h LC50 was 5930 mg/l.