Registration Dossier
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EC number: 203-726-8 | CAS number: 109-99-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Identification
- Display Name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
Type of substance
- Composition:
- mono-constituent substance
- Origin:
- organic
Total tonnage band
- Total range:
- 100 000+ tonnes per annum
REACH
- Registered as:
- FULL
- Submitted:
- Joint Submission
Publication dates
- First published:
- 02-Mar-2011
- Last modified:
- 22-Oct-2020
Chemical safety assessment
- Performed for this substance:
- YES
Compositions open all close all
- Type:
- legal entity composition of the substance
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
- State Form:
- liquid
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
- State Form:
- liquid
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
- State Form:
- liquid
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
- State Form:
- liquid
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
- State Form:
- liquid
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
- State Form:
- liquid
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- boundary composition of the substance
- State Form:
- liquid
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
- State Form:
- liquid
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
- State Form:
- liquid
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
- State Form:
- liquid
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
- State Form:
- liquid
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
- State Form:
- solid: particulate/powder
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
- State Form:
- liquid
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
- State Form:
- liquid
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
- Type:
- legal entity composition of the substance
- State Form:
- liquid
Constituent 1
- Reference substance name:
- Tetrahydrofuran
- EC Number:
- 203-726-8
- EC Name:
- Tetrahydrofuran
- CAS Number:
- 109-99-9
- Molecular formula:
- C4H8O
- IUPAC Name:
- oxolane
Registrants / Suppliers Details open all close all
Registrant / Supplier | Registered | Updated | |||||||||||||||||
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3M Belgium BVBA/SPRL Hermeslaan 7 1831 Diegem Belgium | 2014 | 2018 | |||||||||||||||||
[Confidential] | |||||||||||||||||||
Aceto France 43 avenue marceau 75116 Paris France | 2017 | ||||||||||||||||||
Anthesis (Ireland) Limited 23 The Black Church St. Mary's Place D07 P4AX Dublin Ireland | 2018 | 2018 | |||||||||||||||||
ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France | 2016 | ||||||||||||||||||
ARKEMA PHOTOCURES 420 rue d'Estienne d'Orves 92700 Colombes France | 2018 | ||||||||||||||||||
Ashland Services BV (0311) Noordweg 9 3336 LH Zwijndrecht Netherlands | 2019 | ||||||||||||||||||
Axalta Coating Systems Germany GmbH & Co. KG Christbusch 25 42285 Wuppertal Germany | 2019 | ||||||||||||||||||
BASF Grenzach GmbH Köchlinstr. 1 79639 Grenzach-Wyhlen Germany | 2010 | 2016; 2017 | |||||||||||||||||
BASF Polyurethanes GmbH Elastogranstr. 60 49448 Lemförde Niedersachsen Germany | 2010 | 2016 | |||||||||||||||||
BASF Schwarzheide GmbH Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany | 2010 | 2016 | |||||||||||||||||
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | 2010 | 2014; 2016 | |||||||||||||||||
BCS Only Representative Services Ltd Pembroke House 30 Upper Pembroke Street Dublin 2 Dublin Ireland | 2013 | 2016; 2018; 2020 | |||||||||||||||||
Brenntag Holding GmbH Messeallee 11 45131 Essen Germany | 2018 | ||||||||||||||||||
C.S.B. GmbH Düsseldorfer Str. 113 47809 Krefeld Germany | 2017 | ||||||||||||||||||
CCD (Germany) GmbH Graf-Adolf-Strasse 68 40210 Düsseldorf Germany | 2010 | 2017 | |||||||||||||||||
CCD (Germany) GmbH Graf-Adolf-Strasse 68 40210 Düsseldorf Germany | 2014 | 2017 | |||||||||||||||||
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland | 2020 | ||||||||||||||||||
Chemical Inspection & Regulation Service Limited Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland | 2011 | 2012 | |||||||||||||||||
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland | 2014 | ||||||||||||||||||
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland | 2016 | 2018; 2019 | |||||||||||||||||
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland | 2018 | ||||||||||||||||||
Chemservice S.A. (6HWD) 13, Fausermillen 6689 Mertert Luxembourg | 2018 | ||||||||||||||||||
Chemservice S.A. (H5P7) 13, Fausermillen 6689 Mertert Luxembourg | 2012 | 2016; 2018 | |||||||||||||||||
Chemservice S.A. (VS87) 13, Fausermillen 6689 Mertert Luxembourg | 2019 | ||||||||||||||||||
Chemservice S.A. (YT8K) 13, Fausermillen 6689 Mertert Luxembourg | 2013 | 2016 | |||||||||||||||||
COVANCE CLINICAL DEVELOPMENT SA 043 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5-5 Planta 28050 Madrid Spain | 2018 | ||||||||||||||||||
Covestro Deutschland AG Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany | 2018 | ||||||||||||||||||
CS Regulatory UK Ltd. in its legal capacity as Only Representative of LANXESS Corporation The Old Courthouse St Peters Churchyard DE1 1NN Derby United Kingdom | 2013 | 2017 | |||||||||||||||||
DSM Coating Resins B.V. Ceintuurbaan 5 8022 AW Zwolle Netherlands | 2018 | ||||||||||||||||||
DSM Coating Resins B.V.-OR Ceintuurbaan 5 8022 AW Zwolle Netherlands | 2018 | ||||||||||||||||||
DUBAY Polymer GmbH Frielinghauser Strasse 5 D-59071 Hamm Germany | 2013 | 2014; 2017 | |||||||||||||||||
DuPont de Nemours (Deutschland) GmbH_1 Hugenottenallee 173-175 D-63263 Neu-Isenburg Hesse Germany | 2016 | ||||||||||||||||||
Eastman Chemical B.V. Watermanweg 70 3067 GG Rotterdam Netherlands | 2017 | ||||||||||||||||||
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland | 2018 | ||||||||||||||||||
Evonik Operations GmbH - ME01 Rellinghauser Straße 1-11 45128 Essen Germany | 2018 | ||||||||||||||||||
Evonik Performance Materials GmbH Rellinghauser Strasse 1-11 45128 Essen Germany | 2017 | ||||||||||||||||||
Fisher Scientific UK Ltd Bishop Meadow Rd LE11 5RG Loughborough Leicestershire United Kingdom | 2018 | ||||||||||||||||||
HARKE Chemicals GmbH Xantener Str.1 45479 Mülheim an der Ruhr Germany | 2018 | ||||||||||||||||||
Henkel Global Supply Chain B.V. Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands | 2015 | ||||||||||||||||||
Honeywell Specialty Chemicals Seelze GmbH Wunstorfer Strasse 40 D-30926 Seelze Lower Saxony Germany | 2013 | 2017 | |||||||||||||||||
Hovione FarmaCiencia SA Sete Casas 2674-506 Loures Portugal | 2018 | ||||||||||||||||||
Huntsman (Europe) BV - OR8 Everslaan 45 B-3078 Everberg Belgium | 2019 | ||||||||||||||||||
HUNTSMAN HOLLAND BV Merseyweg 10 3197 KG Botlek-Rotterdam Netherlands | 2016 | ||||||||||||||||||
IGM Resins B.V. Gompenstraat 49 5145 RA Waalwijk Netherlands | 2018 | ||||||||||||||||||
Indorama Ventures Polymers Germany GmbH Philipp Reis Strasse 2 65795 Hattersheim Germany | 2018 | ||||||||||||||||||
INEOS Solvents Marl GmbH Paul-Baumann-Str. 1 45772 Marl Germany | 2010 | 2016 | |||||||||||||||||
ITELYUM Purification S.r.l. Via S. Intini n. 2 27015 Landriano (PV) Italy | 2013 | 2017 | |||||||||||||||||
Knoell NL-OR-047 Agro Business Park 75 6708PV Wageningen Netherlands | 2017 | ||||||||||||||||||
KTR Europe GmbH Mergenthalerallee 77 65760 Eschborn Germany | 2012 | 2017 | |||||||||||||||||
LANXESS Solutions Italy S.r.l. Via Pico della Mirandola, 8 4013 Localita Scalo Latina LT Italy | 2010 | 2017 | |||||||||||||||||
LCNBV-OR-CXV Delftseplein 27E 3013 AA Rotterdam Netherlands | 2015 | ||||||||||||||||||
Lubrizol Advanced Materials Europe B.V.B.A Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium | 2012 | ||||||||||||||||||
Lubrizol Europe Coordination Center BVBA 02 Chaussee De Wavre 1945 Brussels Belgium | 2012 | 2019 | |||||||||||||||||
Lubrizol Europe Coordination Center BVBA 19 Chaussee De Wavre 1945 Brussels Belgium | 2012 | 2020 | |||||||||||||||||
Lubrizol France SAS 25 Quai de France 76100 ROUEN France | 2013 | ||||||||||||||||||
Lubrizol Limited The Knowle, Nether Lane Hazelwwod DE56 4AN Derby Derbyshire United Kingdom | 2017 | ||||||||||||||||||
Lyondell Chemie Nederland B.V. Deltseplein 27E 3013 AA Rotterdam Netherlands | 2010 | 2011; 2013; 2014; 2016 | |||||||||||||||||
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany | 2012 | 2016; 2019 | |||||||||||||||||
MHM Holding GmbH Feldkirchener Straße 15 D-85551 Kirchheim Germany | 2015 | 2017 | |||||||||||||||||
momaja s.r.o. Karolinská 650/1 186 00 Prague 8 Czech Republic | 2011 | ||||||||||||||||||
Monument Chemical Haven 1972 Ketenislaan 3 9130 Kallo Belgium | 2019 | 2020 | |||||||||||||||||
NAM&NAM Europe GmbH Emil-Figge-Str.80 44227 Dortmund(015) Germany | 2017 | ||||||||||||||||||
Novasol S.A. Mechelsesteenweg 455 1950 Kraainem Belgium | 2010 | 2017; 2019 | |||||||||||||||||
Performance Specialty Products Ibérica, S.L.U. Valle de Tamón - Nubledo 33469 Tamón - Carreño Asturias Spain | 2010 | 2010; 2011 | |||||||||||||||||
PPG Europe B.V. - OR1 Amsterdamseweg 14 1422 AD Uithoorn Netherlands | 2016 | ||||||||||||||||||
PPG Europe B.V. - OR3 Amsterdamseweg 14 1422 AD Uithoorn Netherlands | 2016 | ||||||||||||||||||
PPG Industries Italia Srl Società soggetta a direzione e coordinamento da parte di PPG Industries Inc. Via Serra, 1 15028 Quattordio Italy | 2018 | ||||||||||||||||||
Ricardo-AEA Ltd Shoreham Technical Centre BN43 5FG Shoreham-by-Sea West Sussex United Kingdom | 2018 | 2018 | |||||||||||||||||
Sigma-Aldrich Biochemie GmbH Georg-Heyken-Str. 14 21147 Hamburg Germany | 2019 | ||||||||||||||||||
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany | 2013 | 2017 | |||||||||||||||||
SIGMA-ALDRICH CHIMIE SARL 80 Rue de Luzais BP 701 38297 Saint Quentin Fallavier France | 2013 | 2017; 2020 | |||||||||||||||||
Sigma-Aldrich Company Limited The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom | 2013 | 2017; 2020 | |||||||||||||||||
Sigma-Aldrich Ireland Ltd Vale Road . Arklow Co. Wicklow Ireland | 2013 | 2017 | |||||||||||||||||
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom | 2018 | ||||||||||||||||||
The LYCRA Company Nederland B.V. Tunnelweg 95 6468EJ Kerkrade Netherlands | 2010 | 2017 | |||||||||||||||||
The LYCRA Company Nederland BV acting as OR for The LYCRA Company LLC Tunnelweg 95 6468EJ Kerkrade Netherlands | 2017 | 2018 | |||||||||||||||||
The LYCRA Company UK Limited 60 Clooney Road Maydown BT47 6TH Londonderry Northern Ireland United Kingdom | 2010 | 2017 | |||||||||||||||||
TÜV SÜD Iberia S.A.U. (051) Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain | 2010 | 2014; 2017 | |||||||||||||||||
UBE Corporation Europe, S.A.U. (UBE-G) Polígono Industrial El Serrallo, s/n 12100 Castellón Spain | 2018 | ||||||||||||||||||
W. L. Gore & Associates (UK) Ltd. Kirkton South Road Kirkton Campus EH54 7BT Livingston United Kingdom | 2012 | ||||||||||||||||||
W. L. Gore & Associates GmbH Hermann-Oberth-Strasse 22 85640 Putzbrunn Germany | 2012 | ||||||||||||||||||
Will & Co B.V. Dellaertlaan 24 1171 HG Badhoevedorp Netherlands | 2010 | 2010; 2017 | |||||||||||||||||
Yordas GmbH Äußere Nürnberger Str. 62, 91301 Forchheim Germany | 2018 |
Administrative data open all close all
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- 01-2119444314-46-0001
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- 01-2119444314-46-0003
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