Registration Dossier

Toxicological information

Skin irritation / corrosion

Currently viewing:

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2002
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
SIDS Initial Assessment Report for calcium chloride
Year:
2002
Bibliographic source:
Chemicals Evaluation and Research Institute (CERI)

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Test substance: Anhydrous calcium chloride (CaCl2), a white powder,
prepared from calcium chloride dihydrate flakes (Batch No.
Couillet 8/OCT/1985 FLAKES). The test material was solid
at the application time. Upon analysis sample contained:
97.0%
CaCl2, 2.2% NaCl and 0.11% Ca(OH)2.

Test animals

Species:
rabbit

Test system

Type of coverage:
occlusive
Amount / concentration applied:
undiluted
Duration of treatment / exposure:
4 h

Results and discussion

In vivo

Results
Irritation parameter:
overall irritation score
Basis:
mean
Score:
0
Remarks on result:
other: no effects seen

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information
Conclusions:
Classification: not irritating