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Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2002
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
SIDS Initial Assessment Report for calcium chloride
Year:
2002
Bibliographic source:
Chemicals Evaluation and Research Institute (CERI)

Materials and methods

Principles of method if other than guideline:
other method
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rabbit
Strain:
New Zealand White
Sex:
male/female

Administration / exposure

Vehicle:
unchanged (no vehicle)
Doses:
5000 mg/kg bw

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Mortality:
no mortality
Clinical signs:
no adverse effects
Gross pathology:
No significant change was either found by gross necropsy examination.

Applicant's summary and conclusion