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EC number: 233-140-8 | CAS number: 10043-52-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Twelve reliable studies (K2) are available fulfilling overall 16 study records covering different species: 9 crustacean, 2 worms, 1 mollusc and 3 aquatic insects.
Only two studies conducted according to international or national guidelines exposing Daphnia magna (de Groot and Groeneveld 1998) and Ceriodaphnia sp. (Mount et al., 1997) for 48 h to the test item are available. Results indicated estimated EC50s of 2400 mg/L for Daphnia magna and 1830 mg/L for Ceriodaphnia sp. However, the lowest EC50 of 1062 mg/L for crustacean was found in another valid study (Khangarot and Ray 1989), which however was not conducted by a standard method and so deemed less reliable than the aforementioned studies. Two studies reporting the toxicity of the test material to worm, Tubifex tubifex at 96 h (Khangarot, 1991) and Caenorhabditis elegans at 24h (Tatara et al. 1997), showed respectively the lowest and the highest EC50 among all the short-term invertebrates’ studies.
Estimated EC50(96h) for T. tubifex was 780 mg/L and for Caenorhabditis elegans 44400 mg/L. However, these studies were not conducted by standard guidelines and lacked in detail to allow a detailed evaluation of the reliability. Overall, the acute toxicity of reliable K2 studies with invertebrates showed LC50 or EC50 values in the range of 780-44400 mg/L.
There were some K3 studies (6) outside the aforementioned range, however as the quality of these studies could not be verified these were not considered reliable enough for risk assessment purposes.
In conclusion, the short-term invertebrate study selected for risk assessment purposes was the EC50 of 2400 mg/L determined in the most reliable Daphnia magna study performed.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 2 400 mg/L
Additional information
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