Registration Dossier
Registration Dossier
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EC number: 200-662-2 | CAS number: 67-64-1
Biological effects monitoring
Administrative data
- Endpoint:
- biological effects monitoring
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Sufficient documentation. No analytical monitoring, the test containers, however, were covered during the experiments
Data source
Reference
- Reference Type:
- publication
- Title:
- Larvae of a nudibranch mollusc (Phestilla sibogae); Metamorphose when exposed to common organic solvents
- Author:
- Pennington JT, Hadfield MG
- Year:
- 1 989
- Bibliographic source:
- Biol Bull 177: 350-355
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- other method:
The metamorphosis of larvae to juveniles is naturally induced by kairomones of their natural food: corals of the genus Porites (only food of P. sibogae). Organic solvents including acetone were assayed for their capacity to induce metamorphosis of 11 day old larvae of Phestilla sibogae. - GLP compliance:
- not specified
Test material
- Reference substance name:
- Acetone
- EC Number:
- 200-662-2
- EC Name:
- Acetone
- Cas Number:
- 67-64-1
- Molecular formula:
- C3H6O
- IUPAC Name:
- propan-2-one
- Details on test material:
- Test substance: acetone (not further specified)
Constituent 1
Results and discussion
Any other information on results incl. tables
Details on results
Maximum metamorphosis: 83% at 0.25 mol/l.
No information about toxicity of acetone to Phestilla sibogae were
reported.
Applicant's summary and conclusion
- Conclusions:
- Larvae of Phestilla sibogae, competent to metamorphose, were exposed to 0.25 mol/L acetone. After 48h 83% metamorphosis was recorded.
- Executive summary:
Larvae of Phestilla sibogae, competent to metamorphose, were exposed to 0.25 mol/L acetone. After 48h 83% metamorphosis was recorded. The metamorphosis of larvae to juveniles is naturally induced by kairomones of their natural food: corals of the genus Porites (only food of P. sibogae).
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