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Diss Factsheets
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EC number: 233-162-8 | CAS number: 10049-04-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Density
Administrative data
Link to relevant study record(s)
- Endpoint:
- relative density
- Type of information:
- other: secondary source
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- The information does not come from a test report, and the minimum fields required cannot be filled in. The reference cites only endpoint value as a secondary source, and therefore cannot be assigned as reliable. (details on the identity/composition of the substance not provided)
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
- Principles of method if other than guideline:
- No data.
- Type:
- relative density
- Density:
- 2.3
- Remarks on result:
- other: gas density to air
- Executive summary:
This publication cites, as a secondary source, some physico-chemical properties for the substance chlorine dioxide, including a density for the gas state to air of 2.3. Details on the composition of the substance are not specified.
- Endpoint:
- density
- Type of information:
- other: secondary source
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- The information does not come from a test report, and the minimum fields required cannot be filled in. The reference cites only endpoint value as a secondary source and details on composition not specified. Therefore it cannot be assigned as reliable.
- Reason / purpose for cross-reference:
- reference to same study
- Principles of method if other than guideline:
- No data.
- Type:
- density
- Density:
- 1.62
- Temp.:
- 11 °C
- Remarks on result:
- other: at the boiling point
- Type:
- density
- Density:
- 1.765
- Temp.:
- -56 °C
- Remarks on result:
- other: liquid
- Executive summary:
This publication cites, as a secondary source, some physico-chemical properties for the substance chlorine dioxide, including densities of the liquid form, from 1.62 at the b.p. to 1.765 at the m.p.. However, details on composition are not specified.
- Endpoint:
- density
- Type of information:
- other: handbook data
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- The information does not come from a test report, and the minimum fields required cannot be filled in (raw data, no experimental details, no details on the composition of the substance). Data comes from a handbook, and therefore cannot be considered as reliable. However, please note that the data source is cited among "reference books containing peer reviewed physico-chemical data" in the ECHA guidance document on information requirements (R7a).
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
- Principles of method if other than guideline:
- No data.
- Type:
- density
- Density:
- 2.757 g/L
- Temp.:
- 25 °C
- Executive summary:
The peer-reviewed CRC Handbook of Chemistry and Physics provides a density of 2.757 g/L (at 25°C) for the substance Chlorine dioxide. Details on the composition of the substance not specified.
- Endpoint:
- density
- Type of information:
- other: secondary source
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- The information does not come from a test report, and the minimum fields required cannot be filled in. Data comes from a toxicological profile citing other data sources, and therefore cannot be assigned as reliable. However, please note that the secondary source is considered as peer reviewed.
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
- Principles of method if other than guideline:
- No data.
- Type:
- density
- Density:
- 1.64 g/cm³
- Temp.:
- 0 °C
- Remarks on result:
- other: liquid
- Type:
- density
- Density:
- 1.614 g/cm³
- Temp.:
- 10 °C
- Remarks on result:
- other: liquid
- Executive summary:
The peer reviewed ATSDR profile provides density values of 1.640 and 1.614 g/mL, respectively at 0 and 10°C, for the substance Chlorine dioxide, as liquid. However, details on the composition of the substance are not provided.
- Endpoint:
- relative density
- Remarks:
- Other density types indicated (relative vapour density)
- Type of information:
- other: secondary source
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- Data from handbook or collection of data,. They come from a sheet with no reference to data sources, and therefore cannot be assigned as reliable (Details on identity/composition of the substance not provided).
- Reason / purpose for cross-reference:
- reference to same study
- Principles of method if other than guideline:
- No data.
- Type:
- relative density
- Density:
- 1.6
- Temp.:
- 0 °C
- Remarks on result:
- other: (liquid) (water =1)
- Type:
- other: relative vapour density
- Density:
- 2.3
- Remarks on result:
- other: (air = 1)
- Executive summary:
The ICSC provides a relative density of 1.6 for the substance Chlorine dioxide, as liquid at 0°C, and a vapour density of 2.3, compared to air. Details on composition of the substance not specified.
- Endpoint:
- relative density
- Remarks:
- Density types indicated (density)
- Type of information:
- other: secondary source
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- The information does not come from a test report, and the minimum fields required cannot be filled in, such as details on the identity/composition of the test substance. Data comes from a book dedicated to chlorine dioxide, compiling very numerous literature references, but few experimental details are provided. Therefore it cannot be assigned as reliable.
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
- Principles of method if other than guideline:
- No data.
- Type:
- density
- Density:
- 2.4
- Remarks on result:
- other: times heavier than air (gas)
- Type:
- relative density
- Density:
- 1.64
- Temp.:
- 0 °C
- Remarks on result:
- other: liquid [Kaczur and Cawlfield 1992]
- Executive summary:
The Simpson's book, dedicated to chlorine dioxide, provides a density of 2.4 as a gas, and 1.64 as a liquid at 0°C but details on composition of the substance are not specified.
- Endpoint:
- relative density
- Remarks:
- Other density types indicated (vapour density)
- Type of information:
- other: secondary source
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- The information does not come from a test report, and the minimum fields required cannot be filled in. Data comes from an online compilation and reviews using secondary data sources, and therefore cannot be assigned as reliable. However, please note that one of the data sources is cited among "reference books containing peer reviewed physico-chemical data" in the ECHA guidance document on information requirements (R7a), and that the endpoint is cited in the HSDB database as peer reviewed, as well as the IRIS review.
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
- Principles of method if other than guideline:
- No data.
- Type:
- relative density
- Density:
- 1.642
- Temp.:
- 0 °C
- Remarks on result:
- other: (liquid) [1, 4]
- Type:
- relative density
- Density:
- 1.642
- Remarks on result:
- other: [2]
- Type:
- relative density
- Density:
- 1.642
- Remarks on result:
- other: [3]
- Type:
- other: vapour density
- Density:
- 2.34
- Remarks on result:
- other: (air = 1)
- Executive summary:
The HSDB database, the international CICAD review, the EPA IRIS review and the OECD SIDS report provide a peer-reviewed relative density of 1.642 for the substance Chlorine dioxide, under its liquid form at 0°C, cited from the Merck Index handbook, and a vapour density of 2.34, compared to air. However, atmospheric pressure and details on composition of the substance are not specified.
- Endpoint:
- relative density
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is only stable in solution in a particular solvent and the solution density is similar to that of the solvent
- Justification for type of information:
- The substance as registered is always generated in situ as a gas dissolved in water, with concentration not exceeding 2%. The density of this solution will be, essentially, the same as that of pure water (i.e. d=1). Therefore, a further assessment of the density is scientifically unjustified.
Referenceopen allclose all
The gaseous chlorine dioxide can collect in low-lying areas.
Description of key information
Solution of chlorine dioxine generated in-situ at less than 2% in water (as registered): d = 1 (close to the relative density of water)
Key value for chemical safety assessment
- Relative density at 20C:
- 1
Additional information
The substance as registered is always generated in situ as a gas dissolved in water, with concentration not exceeding 2%. No study was conducted to determine the relative density of the substance considering the relative density of the substance as very close to that of pure water, i.e. d=1. Therefore, a further assessment of the relative density is scientifically unjustified and this data is considered as key data for CSA purpose.
Note that a theoretical relative density of the solution was calculated to be 1.008, based on the data compiled from secondary sources on the pure substance (1.64 g/cm3 for pure ClO2liq) and considering a 20 g/L solution.
Other information : Several literature sources provide consistent data for the pure chlorine dioxide: a consensus value of 1.64 for Chlorine dioxide liquid at 0°C, and a mean value of 2.35 for the gas, can be retained.
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