Registration Dossier
Registration Dossier
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EC number: 931-328-0 | CAS number: 7440-44-0
Endpoint summary
Administrative data
Description of key information
- Acute oral toxicity:
Acute toxic class method (OECD 423): LD50 > 2000 mg/kg bw (female rat)
- Acute inhalation toxicity:
Standard acute method: LC50 > 8.5 mg/L
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- LC50
- Value:
- 8 500 mg/m³ air
Additional information
No mortality or toxicity effects were observed in the key study for acute oral toxicity up to the highest dosage of 2000 mg/kg bw. Also no deaths were reported in the key study for acute inhalation toxicity at a tested concentration of 8.5 mg/L. However, body weight loss, respiratory mucous membrane irritancy and - at necropsy - lung discoloration were observed. The LD50 and LC50 were determined to be >2000 mg/kg bw and >8.5 mg/L for the oral and inhalation route, respectively.
Justification for classification or non-classification
Based on the results of the key studies, Activated Carbon - High Density Skeleton (referred to as Steam Activated Carbon) does not need to be classified for acute toxicity when considering the criteria outlined in Annex I of 1272/20008/EC and Annex VI of 67/548/EEC.
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