Registration Dossier
Registration Dossier
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EC number: 267-007-0 | CAS number: 67762-26-9 This substance is identified by SDA Substance Name: C14-C18 and C16-C18 unsaturated alkyl carboxylic acid methyl ester and SDA Reporting Number: 04-010-00.
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Remarks:
- read across on structural analogue
- Adequacy of study:
- key study
- Study period:
- 1994
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Not GLP and not enough details to consider it a full described study. It is scientifically valid to assess the endpoint
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 870.1200 (Acute Dermal Toxicity)
- Deviations:
- no
- GLP compliance:
- not specified
- Test type:
- fixed dose procedure
- Limit test:
- yes
Test material
- Reference substance name:
- Fatty acids, C6-C12 methyl esters
- IUPAC Name:
- Fatty acids, C6-C12 methyl esters
- Details on test material:
- Purity: 99.6%
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Doses:
- 2000 mg/Kg
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- not specified
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The substance was not considered to be an acute dermal toxic
- Executive summary:
LD50 has been tested in a fixed dose test at 2000 mg/kg/bw on rabbit with fatty acids C6 -C12 methyl esters following EPA OPPTS 870.1200 with no sigh of toxicity
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