Lithium 12-hydroxystearate

Repeated dose toxicity: oral

Administrative data

Endpoint:

short-term repeated dose toxicity: oral

Type of information:

read-across based on grouping of substances (category approach)

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

See IUCLID section 13 for category and read across justification

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2020

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 422 (Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test)

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

Lithium myristate

EC Number:

243-743-8

EC Name:

Lithium myristate

Cas Number:

20336-96-3

Molecular formula:

C14H28O2.Li

IUPAC Name:

lithium myristate

Test material form:

other: Solid salt prepared in situ in medicinal white oil for dosing

Details on test material:

- Form of test item: Prepared in situ
- Vehicle: Medicinal White Oil
- Concentration in vehicle: X % w/w

Test animals

Species:

rat

Results and discussion

Effect levels

Remarks on result:

other: Test ongoing

Target system / organ toxicity

Critical effects observed:

not specified

Applicant's summary and conclusion

Conclusions:

The short-term repeat dose toxicity of lithium myristate was determined to be

Executive summary:

The short-term repeat dose toxicity of lithium myristate to rats was determined in a GLP-compliant study following OECD guideline 422.