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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: results of a literature review, published in peer reviewed literature, acceptable with restrictions

Data source

Reference
Reference Type:
publication
Title:
Odor as an aid to chemical safety: odor thresholds compared with threshold limit values and volatiles for 214 industrial chemicals in air and water dilution
Author:
Amoore JE & Hautala E
Year:
1983
Bibliographic source:
J. Appl. Toxicol. 1983 Vol 3 272-290

Materials and methods

Type of study / information:
Literature review of odour thresholds
Endpoint addressed:
respiratory irritation
Principles of method if other than guideline:
The literature has been reviewed to provide quantitative data on the odour thresholds of 214 chemicals. Data on the volatility, solubility, ionisation and water-air distribution ratio at 25ºC are included. A safe dilution factor and an odour safety factor are calculated.
GLP compliance:
no

Test material

Constituent 1
Reference substance name:
Reference substance 001
Cas Number:
77-73-6
Molecular formula:
C10H12
Constituent 2
Reference substance name:
Dicyclopentadiene
IUPAC Name:
Dicyclopentadiene

Method

Ethical approval:
not specified
Details on study design:
no data

Results and discussion

Results:
Air odour threshold dicyclopentadiene: 0.0057±1.9 ppm. Safe dilution factor: 720. Odour safety factor (based on TLV of 5 ppm): 870. More than 90% of distracted persons perceive warning of TLV concentration in the air.

Any other information on results incl. tables

Air-dilution odour thresholds. Threshold limit value: 5 ppm v/v. Volatility at 25ºC: 3600 ppm v/v.

Applicant's summary and conclusion

Conclusions:
Threshold limit value: 5 ppm v/v; Volatility at 25ºC: 3600 ppm v/v; Air odour threshold: 0.0057±1.9 ppm; Safe dilution factor: 720; Odour safety factor: 870; Odour safety class: A (more than 90% of distracted persons perceive warning of TLV concentration in the air)
Executive summary:

A literature search on olfactory and physiochemical properties of volatile substances listed in the Threshold Limit Values (1982) was conducted. The authors compiled, averaged, re-calculated or extrapolated from published information. The values and odour safety class identified for dicyclopentadiene were: Threshold limit value: 5 ppm v/v; Volatility at 25ºC: 3600 ppm v/v; Air odour threshold: 0.0057±1.9 ppm; Safe dilution factor: 720; Odour safety factor: 870; Odour safety class: A (more than 90% of distracted persons perceive warning of TLV concentration in the air).