Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-052-9 | CAS number: 77-73-6
Endpoint summary
Administrative data
Description of key information
The effect of DCPD on the nitrification of soil microorganisms was determined in a GLP-compliant study following OECD guideline 216. No inhibiting effect on the nitrification potential was observed up to a concentration of 1000 mg/kg SDW, the highest concentration tested. The NOEC is therefore considered to be =1000 mg/kg SDW.
The effect of DCPD on earthworm reproduction was determined in a GLP-compliant study following OECD guideline 222. Earthworms were exposed to 6 concentrations of DCPD alongside a control in artificial soil. There were no statistically significant differences in earthworm reproduction in the treatment rates 15.6 to 125 mg DCPD/kg SDW compared to the control. However, at the test item concentration 250 mg DCPD/kg, the earthworm reproduction was statistically significantly reduced and, at the test item concentration 500 mg DCPD/kg soil dry weight, no juveniles were found. Overall, the NOEC of the test item concerning mortality, biomass and reproduction was determined to be 125 mg DCPD/kg SDW and based on reproduction. The EC50 value for reproduction was determined to be 250 mg DCPD/kg SDW.
TLM QSAR modelling was used to estimate the LC50 and EC10 values towards F. candida. The calculated LL50 is 55.475 mg/kg soil dw and NOELR is 10.627 mg/kg soil dw.
TLM QSAR modelling was used to estimate the LL50 and NOELR values towards terrestrial plants. The calculated LL50 for A. sativa is 253.568 mg/kg soil dw and NOELR is 48.576 mg/kg soil dw. The calculated LL50 for B. rapa is 163.717 mg/kg soil dw and NOELR is 31.363 mg/kg soil dw.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
