Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

LC50 fish (96h): 85 mg/l (Oncorhynchus mykiss)

NOEC/LC10 fish (35d): 10 mg/l (Danio rerio)

EC50 Daphnia (48h): > 130 mg/l

NOEC Daphnia (21d): 53 mg/l

EC50 algae (72h): 45 mg/l (growth rate) (Pseudokirchnerella subcapitata)

NOEC algae (72h): 8.2 mg/l (growth rate) (Pseudokirchnerella subcapitata)

EC10 microorganisms (17h): 100 mg/l (Pseudomonas putida)

Additional information

Data availability: For MAA acute as well as chronic studies of sufficient reliability are available for all three trophic levels and also reliable microbial toxicity data.


The aquatic toxicity of methacrylic acid was investigated on all three trophic levels using acute as well as long-term toxicity tests. The results of acute aquatic toxicity tests indicated that the test substance is of low toxicity to aquatic invertebrates (EC50 Daphnia magna: > 130 mg/L) and harmful to fish (LC50 fish (96h): 85 mg/l (Oncorhynchus mykiss) and algae [ECr50 (72h): 45 mg/L, NOEC (72h): 8.2 mg/l with Pseudokirchneriella subcapitata].

In the long-term toxicity tests, fish toxicity in an early life stage test with Danio rerio was the most sensitive endpoint with a NOEC of 10 mg/L, while a 21d Daphnia reproduction test had a NOEC of 53 mg/L.

The microbial EC10 (17h) was determined to be 100 mg/L based on growth inhibition of Pseudomonas putida.

As methacrylic acid has no potential to bioaccumulate in organisms and is readily biodegradable in OECD 301 screening tests ( fulfilling 10 day window) the substance does not have to be classified of environmental hazard acc. EU CLP criteria.