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EC number: 201-204-4 | CAS number: 79-41-4
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- other: not specified
- Principles of method if other than guideline:
- Shake flask method. Concentration of methacrylic acid determined by titration.
- GLP compliance:
- no
- Type of method:
- shake-flask method to: flask method
- Remarks:
- 22°C
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- Origin not known, purity typically >= 98 %
- Analytical method:
- other: acid-base titration
- Key result
- Type:
- log Pow
- Partition coefficient:
- 0.93
- Temp.:
- 22 °C
- pH:
- ca. 2.2
- Details on results:
- data according Sangster, J. (1989):
pH: unspecified, but assumed to be < 2.2 pH of methacrylic acid.
- Hansch and Leo selcted value
- uncertainty: ± 0.20 - pKa = 4.66 - Conclusions:
- The experimental value is log Pow=0.93.
- Executive summary:
The octanol water partition coefficient was tested in a shake flask method. The concentration of methacrylic acid was measured by titration. The experimental value is log Pow=0.93.
Reference
No dimerisation in alcohols has been observed by IR-spectroscopy
Description of key information
The octanol water partition coefficient was tested in by shake flask method and reported with 0.93 at 22 °C . Based on log Pow bioaccumulation in organisms is not expected.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 0.93
- at the temperature of:
- 22 °C
Additional information
Supporting information is available with calculated values of 0.99 (KOWWIN) and -0.28 (method of Hansch & Leo).
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