Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

A guinea pig maximization test (Bruze et al., Contact Dermatitis, 1988) showed a sensitizing effect in one of two batches of a Cyclohexanone resin tested. The same authors also conducted a GPMT with pure Cyclohexanone which showed negative results. A mouse ear swelling test, a guinea pig maximization test and a Buehler test (Gad et al., 1986) showed no skin sensitizing properties for Cyclohexanone.

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

As pure Cyclohexanone showed no sensitising properties in any of the tests available, classification is not warranted.