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Short-term toxicity to fish

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Key value for chemical safety assessment

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For the assessment of acute toxicity of Polychloro copper phthalocyanine (CAS 1328-53-6) to fish experimental data are available. A GLP acute fish test conducted similar to OECD TG 203 was performed by Colour-Chem limited (2000). Cyprinus carpio was used as a test organism. In this limit test no mortality of fish was observed at the end of the test, therefore the 96-h LC50 was determined to be higher than 100 mg/L (nominal). In this study Tween-80 was used as a vehicle. The concentration of the vehicle was 1 g/L.

Additionally, two non-GLP tests conducted according to EPA-660/3-75-009 were performed by Sun Chemical Corporation (1978). In a test conducted with Lepomis macrochirus the 96-h LC50 was determined to be 752.4 mg/l (nominal, rep. no.: 11506-62-01). Whereas in a second test conducted with Oncorhynchus mykiss as a test organism the 96-h LC50 was determined to be 355.6 mg/L (nominal, rep. no.: 11506-03-02). No vehicle was used in both studies.

The test concentrations were not analytically verified.

Overall, based on the available weight-of-evidence of experimental data for the test substance (CAS 1328-53-6) it is considered, that the 96-h LC50 is > 100 mg/L. Therefore, it is considered that CAS 1328-53-6 is with high probability acutely not harmful to fish.