Registration Dossier

Administrative data

Key value for chemical safety assessment

Effects on fertility

Description of key information
- complex metal containing substance
- classification derived using CLP mixture toxicity rules
- solubility of metal constituents

Toxicity to reproduction: other studies

Additional information

The UVCB substance is a complex metal containing substance. Each individual (metal) constituent of this UVCB substance can release soluble ions that can contribute (as ‘relevant’ component) to the mixture toxicity. With knowledge of the elemental composition (IUCLID section 1.4 & 1.2) and mineralogical information on a representative sample (IUCLID Section 4.23), the mixture toxicity rules (EU CLP Guidance Annex I: 3.7.3, and cut-off/Additivity formula Table 3.7.2.) was used to calculate the classification of the UVCB substance.   

The Meclas tool was used to automatically calculate the classification of the intermediate. The tool is based on a database containing the human and environmental classification for each component relevant for classification. The information on the representative mineralogical composition (distribution pattern for each constituent of the UVCB substance) is furthermore incorporated into the tool, so that the elemental composition (in % Total element) is automatically converted into % w/w of compounds/species that are relevant for applying the mixture rules.

Justification for classification or non-classification

Reproductive toxicity: Category 1A (driven by Pb)

The classification derived is applicable to all types of copper slimes. 

The tested sample is representative for copper slime, defined within the concentration ranges outlined under IUCLID section 1.2 (taking typical across companies)

See furthermore attached documents:

  • Please refer to IUCLID section 13 for detailed MeClas printouts with the specified input concentrations and resulting classification. Please visit www.meclas.eu for more information about the tool. MeClas tool version used: 2.5