Registration Dossier

Administrative data

Description of key information

- complex metal containing substance
- solubility of metal constituents
- classification via mixture toxicity rules

Key value for chemical safety assessment

Additional information

The UVCB substance is a complex metal containing substance. Each individual (metal) constituent of this UVCB substance can release soluble ions that can contribute (as ‘relevant’ component) to the mixture toxicity. With knowledge of the elemental composition (IUCLID section 1.2 and 1.4) and mineralogical information on a representative sample (IUCLID Section 4.23), the mixture toxicity rules (EU CLP Guidance Annex I: 3.9.3.4, and cut-off) was used to calculate the classification of the UVCB substance.   

The Meclas tool was used to automatically calculate the classification of the intermediate. The tool is based on a database containing the human and environmental classification for each component relevant for classification. The information on the representative mineralogical composition (distribution pattern for each constituent of the UVCB substance) is furthermore incorporated into the tool, so that the elemental composition (in % Total element) is automatically converted into % w/w of compounds that are relevant for applying the mixture rules.

Justification for classification or non-classification

Specific Target Organ Toxicity (repeated): category 1 (Grade 1 and 2)

 

See furthermore attached documents:

  • Please refer to IUCLID section 13 or CSR Annex I for detailed MeClas printouts with the specified input concentrations and resulting classification. Please visit www.meclas.eu for more information about the tool. MeClas tool version used: 2.5