Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: No GLP study but other quality assurance
Cross-reference
Reason / purpose:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Remarks:
other quality assurance
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Test material was dried before sending to test labs. Sampling of representative samples was made according to Sampling protocol of the REACH Copper Consortium (iuclid 1.4 attachment).
B6 anodic slime from primary smelter (site 1a, not decopperized) (representative, dried, homogenized) lab code: 09TT03746
B6 anodic slime from primary smelter (site 1b, decopperized) (representative, dried, homogenized) lab code: 09TT03745
B6 anodic slime, site 2A lab code: 09TT06661
B6 anodic slime, site 2B lab code: 09TT06662

Results and discussion

Any other information on results incl. tables

Table 5 presents measured pH range and average metal concentrations for the samples. Substances with solubility <10 mg/l are considered low-soluble and those with solubility <1 mg/l are considered poorly soluble /38,43/.

The pH was low especially with the samples 09TT03745, 09TT06661 and 09TT06662. High solubility was obtained for Cu (163-5450 mg/l) and for S (159-3467 mg/l) from all samples. The concentrations of Cu and S were further increasing from the samples 09TT06661 and 09TT06662. In addition, the concentration of Ag from the sample 09TT0375, As from other samples except for 09TT03746, Fe from sample 09TT06662, and Ni from samples 09TT03745 and 09TT03746 was considerable. The standard method involves three tests, which is not enough for a statistical analysis.

 

Table 5: Average water solubility calculated from the 14-16 or 24-26 days shaking tests.

 

 Sample code

09TT03745

09TT03746

09TT06661

09TT06662

 

 

Average or range

Average or range

Average or range

Average or range

pH

 

1.97-2.03

3.98-4.19

2.33-2.36

2.23-2.23

ICP Ag

 

194

1.3

<0.2

0.2

ICP Al

mg/l

0.9

<0.2

2.7

0.7

ICP As

mg/l

755

2.1

61

58

ICP Bi

mg/l

-

-

<1

<1

ICP Ca

mg/l

-

6.4

19

4.3

ICP Cd

mg/l

<0.1

-

-

-

ICP Co

mg/l

6.8

0.3

<0.1

<0.2

ICP Cr

mg/l

0.1

<0.1

<0.2

3.1

ICP Cu

mg/l

5450

1867

163

1173

ICP Fe

mg/l

5.4

<0.2

3.6

82

ICP K

mg/l

<2

<2

<3

<3

ICP Mg

mg/l

1.2

0.3

4.7

0.6

ICP Mn

mg/l

<0.2

<0.2

0.3

1.2

ICP Na

mg/l

7.7

3.6

10

1.2

ICP Ni

mg/l

306

63

0.7

3.7

ICP Pb

mg/l

5.2

5

4.2

2.7

ICP S

mg/l

3467

1081

159

690

ICP Sb

mg/l

2.3

2.7

3.9

3.3

ICP Si

mg/l

0.9

1.6

8.4

3.1

ICP Sn

mg/l

<0.2

<0.2

<0.2

<0.2

ICP Te

mg/l

<0.2

<0.2

2.5

6.7

ICP Zn

mg/l

1.7

0.4

0.1

0.1

 

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): other: poorly soluble in preliminary test
Preliminary test did not indicate any solubility of the substance. Flask method test was performed on representative sample of the UVCB, a complex metal containing substance. Validity of the reported results confirmed by Harlan Lab (V. Gretton, 2010)
Executive summary:

Classic definition of solubility do not apply to the UVCB, who is a complex metal containing substance. The usually accepted meaning in that case is (according to ECHA Guidance on information requirements and chemical safety assessment Chapter R.7a) " the composition of the aqueous solution formed at equilibrium under a defined set of conditions". Temperature and the amount of substance added per unit volume of water (i.e. the loading) are the main factors to consider. It was not always possible to establish equilibrium of all components; therefore, time and type of agitation of the vessels have been described. Aqueous solubilities were reported in mg/l.

For this UVCB, preliminary result demonstrated that substance is poorly soluble in water. Major results from the additional flask test were: with a loading of 5g/100ml, and shaking over 24 -26 days, most constituents showed poor to low solubilities, with the exception of Cu, S, Ni, As, Ag, Pb and Ca (high to moderate) as well as Na, Mg, Co, Sb, Si and Zn (moderate to low). The pH ranged from 1.97 to 2.03, 3.98 to 4.19, 2.33 to 2.33 and 2.23 to 2.23, respectively.

Under these conditions, the report acknowledges that stated solubilities may be higher than reality for some samples (e.g. due to abrasion, difficult to remove tiny undissolved particles, etc).

The reported results from OECD 105 are therefore indicative for the behaviour of the UVCB in water. For the purpose of assessing environmental fate and behaviour of this difficult to test complex metal containing substance, Transformation/dissolution test would however be more appropriate.