Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

Short description of key information on bioaccumulation potential result: 
From 79 to 95% of orally administered acetate-14C was recovered in the form of 14CO2. Only a small amount of the radioactivity was found in the urine and faeces. The radioactivity recovered from excreta during the first 24-h period was considerably less from the males than from the females. Male rats apparently tend to fix more of the radioactivity in the body tissues, and the acetate carbons were not turned over as rapidly as in the females.

Key value for chemical safety assessment

Additional information

Experimental results: From 79 to 95% of orally administered acetate-14C was recovered in the form of 14CO2. Only a small amount of the radioactivity was found in the urine and faeces. The radioactivity recovered from excreta during the first 24-h period was considerably less from the males than from the females. Male rats apparently tend to fix more of the radioactivity in the body tissues, and the acetate carbons were not turned over as rapidly as in the females