Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

There is no data on mutagenicity of silicocalcium. Therefore, read-across approach is utilised. This means the use of information on the mutagenicity of related compounds - such as calcium silicate, which has similar order of water solubility, and releases silicon and calcium.

In vivo and in vitro studies on the mutagenicity of amorphous silicas have not shown relevant positive responses and thus amorphous silica seems to be non-genotoxic. The genetic toxicity of calcium silicate has been tested both in vitro and in vivo,and it has given negative results.


The conclusion is that CaSi can be regarded as likely nongenotoxic.

Short description of key information:
Based on read-across data from silcia and silicates, there are no indications of genotoxicity. The conclusion is that CaSi can be regarded as likely nongenotoxic.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

Conclusion: No classification for mutagenicity or further testing is suggested.