Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 915-037-6 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
There are no data on sensitising effects of silicocalcium. Therefore the read-across approach from related compounds is used.
The surface of silicocalcium is composed mainly of silicon and calcium rich oxides. Silicon is released from CaSi at similar or somewhat lower levels than from amorphous silicon dioxide. The released silicon species from silica and silicates, as well as from calcium silicon, is silicic acid.
No sensitisation by silica or silicates (including calcium and aluminium silicates), which are used e. g. in cosmetics, has bee found. The weight-of evidence suggests that CaSi is not sensitising.
Migrated from Short description of key information:
There were no animal or human data on skin sensitisation with silicocalcium. Therefore, the weight of evidence approach is utilised in which the information on the toxicity of related compounds are used.
Respiratory sensitisation
Endpoint conclusion
- Additional information:
see above
Justification for classification or non-classification
Conclusion: Silicocalcium is not sensitising to skin or respiratory system. No further tests are suggested.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
