Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 271-846-8 | CAS number: 68609-97-2
Endpoint summary
Administrative data
Description of key information
Additional information
A study was conducted to assess the toxicity of the test substance, Oxirane mono (C12-C14) glycidyl ether; CAS
RN 68609-97-2, to Rainbow Trout in a 96-hour semi-static test.
Test concentations were determined by a preliminary range-finding test. The loading rate concentrations chosen for the range-finding test (1, 10 and 100 mg/L) were administered to the test system, Rainbow Trout, in laboratory fresh water. A main test was run using the test material at loading rate concentration of 10, 18, 32, 56 and 100 mg/L, which was administered to the test system in laboratory fresh water. The test was terminated after 96 hours of exposure. A 100% survival rate was observed in control fish, and for all loading rate concentrations used . Based on observation, the 96-hour median lethal loading rate (LL50) of the substance was determined to be >100 mg/L. The NOEC (No Observed Effect Concentration) for survival was determined to be = 100 mg/L.
A study was conducted to determine the toxic effects of Alkyl (C12-C14) glycidyl ether; CAS RN 68609-97-2 on the growth of the freshwater algae Selenastrum capricornutum in a 72-hour test. The test substance concentrations of 500, 1000, 2000, 4000, and 8000 mg/L (based on a preliminary range-finding test) were administered to the test system, Selenastrum capricornutum, in sterile medium. For each test concentration, three test containers containing the freshwater algae (initial cell density of 10,000 cells/mL) were treated with the appropriate concentration of the test substance. A control group consisted of six test containers containing sterile medium and the test culture only. A positive control group consisted of three replicates treated with 10 mg/L potassium dichromate. The cell density in each test and control container was measured daily using a hemacytometer. The pH of each test and control container was determined at test termination. The test was terminated after 72 ± 2 hours of exposure. The mean cell counts of the test concentration containers were compared to the control counts. The test concentration that resulted in 50% inhibition (IC50) was determined to be 843.75 mg/L with 95% confidence limits of 582.44-1097.71 mg/L. The NOEC (No Observed Effect Concentration) was determined to be 500 mg/L.
A study was conducted to determine the toxic effects of Alkyl (C12-C14) glycidyl ether; CAS RN 68609-97-2 on Daphnia magna in a 48-hour test. In the main test, twenty daphnids (2 replicates of 10 animals) were exposed to Water Accommodated Fractions (WAFs) of the test item over a range of nominal loading rates of 1.0, 1.8, 3.2, 5.6, 10, 18, 32, 56 and 100 mg/l for 48 hours under at a temperature of approximately 20°C under static test conditions.
The 48-Hour EL50 for the test item to Daphnia magna based on nominal loading rates was 7.2 mg/l loading rate WAF with 95% confidence limits of 4.1 - 12 mg/l loading rate WAF. The No Observed Effect Loading rate was 1.8 mg/l loading rate WAF.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
