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Environmental fate & pathways

Field studies

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Administrative data

Endpoint:
field studies
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature
Remarks:
Original reference source not checked.

Data source

Reference
Reference Type:
publication
Title:
Application of the maximum cumulative ratio (MCR) as a screening tool for the evaluation of mixtures in residential indoor air.
Author:
De Brouwere KD, Cornelis C, Arvanitis A, Terry Brown T, Crump D, Harrison P, Jantunen M, Price P, Torfs R.
Year:
2014
Bibliographic source:
Sci Tot Env 479–480, 267–276.

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Study to explore using the MCR approach,whether health risks due to indoor air pollution are dominated by one substance or are due to concurrent exposure to various substances. The MCR (maximum cumulative ratio) method allows the categorisation of mixtures according to whether the mixture is of concern for toxicity and if so whether this is driven by one substance or multiple substances. Analysis was undertaken on monitoring data of four European indoor studies (giving five datasets), involving 1800 records of indoor air or personal exposure. Only one study included data on 2-butoxyethanol.
GLP compliance:
no
Type of measurement:
Indoor air concentration
Media:
Air

Test material

Constituent 1
Chemical structure
Reference substance name:
2-butoxyethanol
EC Number:
203-905-0
EC Name:
2-butoxyethanol
Cas Number:
111-76-2
Molecular formula:
C6H14O2
IUPAC Name:
2-butoxyethanol
Details on test material:
no further information available

Results and discussion

Any other information on results incl. tables

Measurements of 2 -butoxyethanol were reported in the EXPOLIS data base as follows:

  • Personal measurements (Helsinki, Athens, Prague, Oxford, Basel): average concentrations: 6.6µg/m³, 70% of measurements below limit of reporting.
  • Indoor residential (Helsinki, Athens, Prague, Milan, Oxford, Basel): average concentrations: 11µg/m³, 63% of measurements below limit of reporting.

Reference: Jantunen MJ, Hanninen O, Katsouyanni K, Knoppel H, Kuenzli N, Lebret E, et al. Air pollution exposure in European cities: the “EXPOLIS” study. J Expo Anal Environ Epidemiol 1998;8:495–518

Applicant's summary and conclusion

Executive summary:

A secondary source of information reported the results of two indoor air quality studies that detected 2 -butoxyethanol in residential homes at concentrations in the range 6.6 -11µg/m³. It was only detected however in around one third of homes. the original source of information was not checked.