Registration Dossier
Registration Dossier
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EC number: 203-905-0 | CAS number: 111-76-2
Field studies
Administrative data
- Endpoint:
- field studies
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Remarks:
- Original reference source not checked.
Data source
Reference
- Reference Type:
- publication
- Title:
- Application of the maximum cumulative ratio (MCR) as a screening tool for the evaluation of mixtures in residential indoor air.
- Author:
- De Brouwere KD, Cornelis C, Arvanitis A, Terry Brown T, Crump D, Harrison P, Jantunen M, Price P, Torfs R.
- Year:
- 2 014
- Bibliographic source:
- Sci Tot Env 479–480, 267–276.
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Study to explore using the MCR approach,whether health risks due to indoor air pollution are dominated by one substance or are due to concurrent exposure to various substances. The MCR (maximum cumulative ratio) method allows the categorisation of mixtures according to whether the mixture is of concern for toxicity and if so whether this is driven by one substance or multiple substances. Analysis was undertaken on monitoring data of four European indoor studies (giving five datasets), involving 1800 records of indoor air or personal exposure. Only one study included data on 2-butoxyethanol.
- GLP compliance:
- no
- Type of measurement:
- Indoor air concentration
- Media:
- Air
Test material
- Reference substance name:
- 2-butoxyethanol
- EC Number:
- 203-905-0
- EC Name:
- 2-butoxyethanol
- Cas Number:
- 111-76-2
- Molecular formula:
- C6H14O2
- IUPAC Name:
- 2-butoxyethanol
- Details on test material:
- no further information available
Constituent 1
Results and discussion
Any other information on results incl. tables
- Personal measurements (Helsinki, Athens, Prague, Oxford, Basel): average concentrations: 6.6µg/m³, 70% of measurements below limit of reporting.
- Indoor residential (Helsinki, Athens, Prague, Milan, Oxford, Basel): average concentrations: 11µg/m³, 63% of measurements below limit of reporting.
Measurements of 2 -butoxyethanol were reported in the EXPOLIS data base as follows:
Reference: Jantunen MJ, Hanninen O, Katsouyanni K, Knoppel H, Kuenzli N, Lebret E, et al. Air pollution exposure in European cities: the “EXPOLIS” study. J Expo Anal Environ Epidemiol 1998;8:495–518
Applicant's summary and conclusion
- Executive summary:
A secondary source of information reported the results of two indoor air quality studies that detected 2 -butoxyethanol in residential homes at concentrations in the range 6.6 -11µg/m³. It was only detected however in around one third of homes. the original source of information was not checked.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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