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EC number: 229-176-9 | CAS number: 6422-86-2
In an acute oral toxicity study, five rats per sex were administered a single dose of di (2-ethylhexyl) terephthalate by oral gavage at a dose level of 5000 mg/kg bw. The rats were observed for mortality and adverse clinical signs for a period of 14 days. No mortality was observed in the study. Clinical signs of toxicity were limited to oily, unkempt inguinal hair for all animals on Days 1 and 2 of the study, and yellow discolored inguinal hair for two female rats on Day 1. No other clinical abnormalities were noted throughout the study. All rats gained weight over the 14-day observation period. Based on the results of this study, the LD50 per os of di (2-ethylhexyl) terephthalate is greater than 5000 mg/kg bw.
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