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Dissociation constant

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Read across to structural analogue Edetic acid. For justification of read across see IUCLID section 13. The dissociation constant was estimated from the measured acidity constant (at 20 degree C). A range of -0.12 to 10.44 was estimated for H4EDTA with different electrolytes, ion strength and electrodes: pKa1: 8.85 to 10.44, pKa2: 6.07 to 6.28, pKa3: 2.3 to 2.7, pK4: 2 to 2.2, pK5: 1.4, pK6: -0.12.

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