Registration Dossier
Registration Dossier
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EC number: 201-185-2 | CAS number: 79-20-9
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Methyl acetate need not to be classified as toxic to fish
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 250 mg/L
Additional information
In a 96-h acute toxicity study according to OECD 203, zebra fish (Brachidanio rerio) were exposed to methyl acetate at nominal concentrations of 0, 100, 250, 350, 500, 1000, 1800 and 5000 mg a.i./L} under static conditions. The 96-h LC50was 250 - 350 mg a.i./L. The LC0and LC100values, based on mortality, were 250 and 500 mg a.i./L, respectively. Sublethal effects of protruding gills, increased and decreased breathing, passive sinking, swimming at the surface, increased and decreased activity, edema, tremours, convulsions were observed in the groups exposed to 350, 500, 1000, 1800, and 5000 mg a.i./L.
The 96-h LC50was 250 - 350 mg a.i./L. The lower value is given as key value.
LC50 for marine fish is not available.
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