Registration Dossier
Registration Dossier
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EC number: 208-863-7 | CAS number: 544-17-2
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Studies using calcium formate are not known to exist, but results from a supporting formate salt may be read across.
Potassium diformate (1:2) was not sensitizing in a Guinea pig maximization test (10 controls, 20 test animals) that was conducted according to OECD 406 and under GLP. The concentration of the test substance was 0.5 and 15% dissolved in purified water during induction and 10% at challenge; the test concentrations were selected following preliminary studies. No skin reactions were seen in the 20 test and 10 control animals at 24 or 48 hours after challenge. Potassium diformate, therefore, is not a skin sensitiser (Covance Laboratories, 1998).
The study is considered to be full valid and suitable for assessment. This result can be extrapolated to calcium diformate.
Migrated from Short description of key information:
Formic acid and formate salts including calcium diformate lack a sensitising potential.
Justification for classification or non-classification
No classification required. Criteria of regulations 67/548/EC and 1272 /2008/EC not met.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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