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Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Not available
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Secondary literature source, rating as per REACH Guidance document 7a. (Endpoint-specific guidance).
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
1970

Materials and methods

Study type:
study with volunteers
Principles of method if other than guideline:
Method followed unknown, data from handbook.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Glycerides, C8-18 and C18-unsatd.
EC Number:
266-946-3
EC Name:
Glycerides, C8-18 and C18-unsatd.
Cas Number:
67701-28-4
Molecular formula:
Triglycerides containing a glycerol backbone esterified to fatty acids with a carbon chain length of C8-18 as well as unsaturated C18 fatty acids
IUPAC Name:
Tri(C8-18 and C18-unsatd. fatty acyl)glycerol
Details on test material:
- Name of test material (as cited in study report): Coconut oil (CAS N° 8001-31-8, EC N° 232-282-8); under the SDA nomenclature, the name of this substance is ‘Glycerides, C8-18 and C18-unsatd.’

Method

Type of population:
general
Subjects:
No information
Ethical approval:
not specified
Route of exposure:
dermal
Reason of exposure:
intentional
Exposure assessment:
not specified

Results and discussion

Clinical signs:
No data

Any other information on results incl. tables

None

Applicant's summary and conclusion

Conclusions:
The substance is not irritating to human skin.
Executive summary:

According to the Biotech Index, coconut oil is not irritating to human skin after 4 h of exposure.