Registration Dossier

Administrative data

Key value for chemical safety assessment

Additional information

All tests with sodium bromide were negative (in vitro bacterial mutation test,in vitro mammalian cytogenetic test,in vitro Unscheduled DNA Synthesis in mammalian cells).

Based on all these results, sodium bromide does not need to be classified with regard to mutagenicity.

Sodium bromide is an inorganic salt that dissociates to its composite ions in aqueous solutions at environmental pH and temperature. Comparison of the available data on the various bromide salts have shown that the bromide ion is the relevant ion for determination of the toxicological profile with simple cations such as potassium, sodium or ammonium, that are ubiquitous in nature, having little or no influence on the bromide ion properties. It is therefore justified to read-across data from other inorganic bromide salts to sodium bromide.


Short description of key information:
All tests available with sodium bromide were negative (in vitro bacterial mutation test, in vitro mammalian cytogenetic test, in vitro Unscheduled DNA Synthesis in mammalian cells).

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

The substance in not mutagenic.