Registration Dossier
Registration Dossier
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EC number: 231-599-9 | CAS number: 7647-15-6
Endpoint summary
Administrative data
Description of key information
Case studies are presented for humans exposed to bromide containing substances (usually prescribed or over-the-counter medications). These case studies detail the effects of excessive bromide intake with symptoms of neurotoxicity being the most prevalent. The observed effects were reversible in almost all cases following removal of the source of bromide intake.
Additional information
Bromide salts are known central nervous system depressants and bromide-containing medications have been in use for 150 years for the treatment of epilepsy and as effective anticonvulsants. Bromide containing medications are still available today as prescription drugs, and as some over-the-counter medications such as bromopheniramine and dextromethorphan bromide. Case studies of bromide intoxication, also known as bromism, have been described in a number of medical and scientific publications in recent years.
Case studies are presented for humans exposed to bromide containing substances (usually prescribed or over-the-counter medications). These case studies detail the effects of excessive bromide intake with symptoms of neurotoxicity being the most prevalent. The observed effects were reversible in almost all cases following removal of the source of bromide intake.
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