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EC number: 919-284-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- 11-May-2001 to 8-Jun-2001
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: This robust summary has a reliability rating of 2 because the study followed a standard test guideline, there were no deviations from the protocol, however it was not conducted under GLP.
- Justification for type of information:
- A discussion and report on the read across strategy is given as an attachment in IUCLID Section 13
- Reason / purpose for cross-reference:
- read-across: supporting information
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Inoculum used as the source of the microorganisms was an aliquot of fresh activated sludge from a domestic wastewater treatment facility in New Jersey, USA.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- ca. 50 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Test material was tested in triplicate, controls and blanks were tested in duplicate. The amount of oxygen consumed by microorganisms from the oxidation of the test material was continuously monitored by an automated respirometer during the 28-day test period. Test material concentration was approximately 50mg/L. Sodium benzoate (positive control) concentration was 50mg/L. All test vessels were stirred constantly for 28 days using magnetic stir bars and plates.
- Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (O2 consumption)
- Value:
- 1.79
- St. dev.:
- 2.29
- Sampling time:
- 5 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 5.73
- St. dev.:
- 0.55
- Sampling time:
- 6 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 29
- St. dev.:
- 1
- Sampling time:
- 7 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 42.63
- St. dev.:
- 2.02
- Sampling time:
- 13 d
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 49.56
- St. dev.:
- 0.37
- Sampling time:
- 28 d
- Details on results:
- Test material was inherently biodegradable. Half-life was approximately 4 weeks. By day 28, approximately 49.6% degradation of the test material was observed. 10% biodegradation was achieved on approximately day 7, 50% biodegradation was not achieved. By day 14, >60% biodegradation of positive control was observed, which meets the guideline requirement. No excursions from the protocol were noted.
Biodegradation was based on oxygen consumption and the theoretical oxygen demand of the test material as calculated using results of an elemental analysis of the test material. - Results with reference substance:
- Sodium benzoate, the positive control, achieved 88.7% with a standard deviation of 2.71% degradation after 28 days, and therefore this test may be considered valid.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- inherently biodegradable
- Conclusions:
- Hydrocarbons, C10, aromatics, <1% naphthalene, biodegraded 49.6% after 28 days under the conditions of the study and is inherently biodegradable.
- Executive summary:
Hydrocarbons, C10, aromatics, <1% naphthalene, biodegraded 49.6% after 28 days under the conditions of the study and is inherently biodegradable.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- Dec 2000 to Jan 2001
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: This robust summary has a reliability rating of 2 because the study followed a standard test guideline, there were no deviations from the protocol, however it was not conducted under GLP.
- Justification for type of information:
- The justification for read across is provided as an attachment in IUCLID Section 13.
- Reason / purpose for cross-reference:
- read-across: supporting information
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Inoculum used as the source of the microorganisms was an aliquot of fresh activated sludge from a domestic wastewater treatment facility in New Jersey, USA.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- ca. 50 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Test material was tested in triplicate, controls and blanks were tested in duplicate. The amount of oxygen consumed by microorganisms from the oxidation of the test material was continuously monitored by an automated respirometer during the 28-day test period. Test material concentration was approximately 50mg/L. Sodium benzoate (positive control) concentration was 50mg/L. All test vessels were stirred constantly for 28 days using magnetic stir bars and plates.
- Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (O2 consumption)
- Value:
- 2.44
- St. dev.:
- 2.73
- Sampling time:
- 4 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 46.05
- St. dev.:
- 5.04
- Sampling time:
- 5 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 51.43
- St. dev.:
- 3.09
- Sampling time:
- 7 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 60.04
- St. dev.:
- 2.32
- Sampling time:
- 17 d
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 69.99
- St. dev.:
- 8.99
- Sampling time:
- 28 d
- Details on results:
- Test material was readily biodegradable. Half-life was <2 weeks. By day 28, 69.99% degradation of the test material was observed. 10% biodegradation was achieved on approximately day 5, 50% biodegradation on approximately day 7.
By day 14, >60% biodegradation of positive control was observed, which meets the guideline requirement. No excursions from the protocol were noted. - Results with reference substance:
- Sodium benzoate, the positive control, achieved 94.42% with a standard deviation of 11.42% degradation after 28 days, and therefore this test may be considered valid.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable, but failing 10-day window
- Conclusions:
- Hydrocarbons, C10-C13, aromatics, <1% naphthalene, a multi-component substance, biodegraded to an extent of 70% after 28 days. The data support characterizing the test substance as rapidly biodegradable, readily biodegradable, not expected to persist in the environment under aerobic conditions. Although it did not meet the 10 -day window requirement, it is characterized as readily biodegradable because the criteria is not applied to multi-component substances when assessing their ready biodegradability.
- Executive summary:
Hydrocarbons, C10-C13, aromatics, <1% naphthalene, a multi-component substance, biodegraded to an extent of 70% after 28 days. The data support characterizing the test substance as rapidly biodegradable, readily biodegradable, not expected to persist in the environment under aerobic conditions. Although it did not meet the 10 -day window requirement, it is characterized as readily biodegradable because the criteria is not applied to multi-component substances when assessing their ready biodegradability.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 19-Dec-2000 to 16-Jan-2001
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: This robust summary has a reliability rating of 2 because the study followed a standard test guideline, there were no deviations from the protocol, however it was not conducted under GLP.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- no
- Remarks:
- This study was done in the spirit of the GLPs.
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Inoculum used as the source of the microorganisms was an aliquot of fresh activated sludge from a domestic wastewater treatment facility in New Jersey, USA.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- ca. 50 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Test material was tested in triplicate, controls and blanks were tested in duplicate. The amount of oxygen consumed by microorganisms from the oxidation of the test material was continuously monitored by an automated respirometer during the 28-day test period. Test material concentration was 50mg/L. Sodium benzoate (positive control) concentration was approximately 50mg/L. All test vessels were stirred constantly for 28 days using magnetic stir bars and plates.
- Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (O2 consumption)
- Value:
- 2.9
- St. dev.:
- 3.3
- Sampling time:
- 5 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 15.9
- St. dev.:
- 9.47
- Sampling time:
- 6 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 50.69
- St. dev.:
- 1.75
- Sampling time:
- 17 d
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 57.95
- St. dev.:
- 0.71
- Sampling time:
- 28 d
- Details on results:
- Test material was inherently biodegradable. Half-life was approximately 17 days. By day 28, approximately 58.0% degradation of the test material was observed. 10% biodegradation was achieved on approximately day 6, 50% biodegradation on approximately day 16.
By day 14, >60% biodegradation of positive control was observed, which meets the guideline requirement. No excursions from the protocol were noted.
Biodegradation was based on oxygen consumption and the theoretical oxygen demand of the test material as calculated using results of an elemental analysis of the test material. - Results with reference substance:
- Sodium benzoate, the positive control, achieved 94.42% with a standard deviation of 11.42% degradation after 28 days, and therefore this test may be considered valid.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- inherently biodegradable
- Conclusions:
- Hydrocarbons, C10, aromatics, >1% naphthalene, are inherently biodegradable under the conditions of the study and are not expected to persist in the environment under aerobic conditions.
- Executive summary:
Hydrocarbons, C10, aromatics, >1% naphthalene, are inherently biodegradable under the conditions of the study and are not expected to persist in the environment under aerobic conditions.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- 20-Oct-1994 to 17-Nov-1994
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: This robust summary has a reliability rating of 2 because the study followed a standard test guideline, there were no deviations from the protocol, however it was not conducted under GLP.
- Justification for type of information:
- A discussion and report on the read across strategy is given as an attachment in IUCLID Section 13
- Reason / purpose for cross-reference:
- read-across: supporting information
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Inoculum used as the source of the microorganisms was an aliquot of fresh activated sludge from a domestic wastewater treatment facility in New Jersey, USA.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- ca. 35 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Test material was tested in triplicate, controls and blanks were tested in duplicate. The amount of oxygen consumed by microorganisms from the oxidation of the test material was continuously monitored by an automated respirometer during the 28-day test period. Test material concentration was 35mg/L. Sodium benzoate (positive control) concentration was approximately 50mg/L. All test vessels were stirred constantly for 28 days using magnetic stir bars and plates.
- Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 2 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 17.94
- Sampling time:
- 3 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 52.67
- Sampling time:
- 5 d
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 60.74
- St. dev.:
- 3.43
- Sampling time:
- 28 d
- Details on results:
- Test material was readily biodegradable. Half-life was <1 week. By day 28, 60.7% degradation of the test material was observed. 10% biodegradation was achieved on approximately day 3, 50% biodegradation on approximately day 5.
By day 14, >60% biodegradation of positive control was observed, which meets the guideline requirement. No excursions from the protocol were noted. - Results with reference substance:
- Sodium benzoate, the positive control, achieved 97.33% with a standard deviation of 0.72% degradation after 28 days, and therefore this test may be considered valid.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable, but failing 10-day window
- Conclusions:
- Hydrocarbons, C10 -C13, aromatics, >1% naphthalene, a multi-component substance, biodegraded to an extent of 61% after 28 days. The data support characterizing the test substance as rapidly biodegradable, readily biodegradable, not expected to persist in the environment under aerobic conditions. Although it did not meet the 10 -day window requirement, it is characterized as readily biodegradable because the criteria is not applied to multi-component substances when assessing their ready biodegradability.
- Executive summary:
Hydrocarbons, C10-C13, aromatics, >1% naphthalene, a multi-component substance, biodegraded to an extent of 61% after 28 days. The data support characterizing the test substance as rapidly biodegradable, readily biodegradable, not expected to persist in the environment under aerobic conditions. Although it did not meet the 10 -day window requirement, it is characterized as readily biodegradable because the criteria is not applied to multi-component substances when assessing their ready biodegradability.
Referenceopen allclose all
% Degradation* | Mean % Degradation | |
Sample | (day 28) | (day 28) |
Test Material | 49.8, 49.3 | 49.6 |
Na Benzoate | 89.6, 85.7, 90.9 | 88.7 |
* replicate data
% Degradation* | Mean % Degradation | |
Sample | (day 28) | (day 28) |
Test Material | 57.1, 58.1, 58.5 | 57.95 |
Na Benzoate | 86.4, 107.5, 89.4 | 94.4 |
* replicate data
Description of key information
There is data available for this substance. Additionally, key data is available for the following structural analogues: Hydrocarbons, C10, aromatics, <1% naphthalene, Hydrocarbons, C10-C13, aromatics, <1% naphthalene and Hydrocarbons, C10-C13, aromatics, >1% naphthalene. The data for these substances is presented in the dossier. The data is read across to these substances based on analogue read across and a discussion and report on the read across strategy is provided as an attachment in IUCLID Section 13.
Based on the available data, this substance is considered readily biodegradable. Key information is summarised below:
Hydrocarbons, C10-C13, aromatics, <1% naphthalene, biodegraded to an extent of 70% after 28 days under the conditions of the study and is considered readily biodegradable.
Hydrocarbons, C10 -C13, aromatics, >1% naphthalene, biodegraded to an extent of 61% after 28 days under the conditions of the study and is considered readily biodegradable.
Hydrocarbons, C10, aromatics, <1% naphthalene, biodegraded 49.6% after 28 days under the conditions of the study and is therefore considered inherently biodegradable.
Hydrocarbons, C10, aromatics, >1% naphthalene, biograded 57.95% after 28 days under the conditions of the study and is therefore considered inherently biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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