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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Link to relevant study record(s)

Description of key information

Titanium species show a little tendency to accumulate in organisms; an inverse relationship between water concentration and BCF was found.

Key value for chemical safety assessment

BCF (aquatic species):
352 L/kg ww

Additional information

No experimental data on bioaccumulation of titanium tetrachloride can be obtained experimentally as it hydrolyzes within milliseconds completely to hydrogen chloride (CAS 7647-01-0), which is considered irrelevant due to its high natural background concentrations, and to titanium dioxide (CAS 13463-67-7), which is sparingly water soluble. Experimental investigation (Frederici et al 2007) revealed enrichment of undefined titanium species in fish. The higher the medium concentration the lower was the measured BCF. About 352 L/kg ww was established for low concentrations (0.1 mg/L) and lipid-rich organs, while about 272 L/kg ww in steady state was found for muscles (lower in gills). As due to the experimental set-up (measurement at days 7 and 14 only) no equilibrium was detectable, further enrichment in lipid-rich tissues can not be excluded. Nonetheless the experimental data do not raise concerns with regard to bioaccumulation.