Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-599-4 | CAS number: 143-33-9
Endpoint summary
Administrative data
Description of key information
Additional information
Hydrogen cyanide and soluble cyanide salts are not bioaccumulative in aquatic or terrestrial environments. The octanol-water partitioning coefficient (Kow) for hydrogen cyanide is not indicative of the potential for bioaccumulation, i.e., the log Kow of -0.25 for hydrogen cyanide is substantially less than the threshold log Kow of 3 or more that is indicative of the potential for bioaccumulation (ECHA, May 2008, Guidance on information requirements and chemical safety assessment, Chapter R.7, Endpoint-specific guidance, Section R.7.10.3.4). Callahan et al. (United States Environmental Protection Agency, 1979) state "there is little potential for bioaccumulation of hydrogen cyanides." A predicted BCF = 3.162 L/kg wet weight (log BCF = 0.500) was obtained from BCFBAF version 3.00, a QSAR model within U.S. EPA's EPISuite program; the BCF predictions of this model may be applied, for screening purposes, to organisms in aquatic and terrestrial environments. This predicted BCF is substantially below the threshold BCF values of >2000 L/kg and >5000 L/kg for classification as PBT and vPvB, respectively (ECHA, May 2008. Guidance on information requirements and chemical safety assessment, Chapter R.11, PBT Assessment, Table R.11 -1).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
