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Environmental fate & pathways

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Hydrogen cyanide and soluble cyanide salts are not bioaccumulative in aquatic or terrestrial environments. The octanol-water partitioning coefficient (Kow) for hydrogen cyanide is not indicative of the potential for bioaccumulation, i.e., the log Kow of -0.25 for hydrogen cyanide is substantially less than the threshold log Kow of 3 or more that is indicative of the potential for bioaccumulation (ECHA, May 2008, Guidance on information requirements and chemical safety assessment, Chapter R.7, Endpoint-specific guidance, Section R.7.10.3.4). Callahan et al. (United States Environmental Protection Agency, 1979) state "there is little potential for bioaccumulation of hydrogen cyanides." A predicted BCF = 3.162 L/kg wet weight (log BCF = 0.500) was obtained from BCFBAF version 3.00, a QSAR model within U.S. EPA's EPISuite program; the BCF predictions of this model may be applied, for screening purposes, to organisms in aquatic and terrestrial environments. This predicted BCF is substantially below the threshold BCF values of >2000 L/kg and >5000 L/kg for classification as PBT and vPvB, respectively (ECHA, May 2008. Guidance on information requirements and chemical safety assessment, Chapter R.11, PBT Assessment, Table R.11 -1).