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Bromine in contact to water forms a mixture of brominated oxidants such as hydrobromic and hypobromous acids (See Annex VIII Section 9.2.2.1 Hydrolysis). Oxidants produced from bromine in water are known to be very toxic to aquatic organisms and very reactive. This fact is reflected in the EU Classification and Labelling of bromine as it is classified/labelled with the symbol “N” (dangerous for the environment) and the risk phrase “R50” (very toxic to aquatic organisms). Inorganic bromide is the principal ultimate degradant from reaction of these species. Bromide occurs naturally in the environment. In the presence of natural waters or test media containing biological molecules, other brominated oxidant species may also be formed.