Registration Dossier

Administrative data

Endpoint:
dermal absorption
Type of information:
other: read-across to (Q)SAR based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
other: QSAR Database
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Guideline:
other: REACH guidance on QSARs R.6, May/July 2008
Principles of method if other than guideline:
Danish (Q)SAR database report

Test material

Constituent 1
Chemical structure
Reference substance name:
2-ethylhexyl palmitate
EC Number:
249-862-1
EC Name:
2-ethylhexyl palmitate
Cas Number:
29806-73-3
Molecular formula:
C24H48O2
IUPAC Name:
2-ethylhexyl palmitate
Details on test material:
- Name of test material (as cited in study report): Hexadecanoic acid, 2-ethylhexyl ester

Results and discussion

Absorption in different matrices:
Dermal absorption of 2-ethylhexyl palmitate was predicted to be 0.00001 mg/cm2/event (very low).

Applicant's summary and conclusion