Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 926-771-1 | CAS number: -
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Description of key information
No effects on fertility or adverse effects to the development of offspring were observed in the OECD 421 screening test on read-across target AES fibres.
Additional information
FMMVF fibres are inorganic fibre of very low biological activity. FMMVF fibres do not translocate after intake (ingestion or inhalation). Due to these characteristics it is evaluated that exposure of males and females to FMMVF fibres in a pre-mating period will not affect their fertility. It is assessed that human exposure to FMMVF fibres will not impair human fertility. Consequently, a fertility toxicity study is waived because it is scientifically unjustified.
Short description of key information:
It is assessed that exposure to FMMVF fibres will not impair human
fertility. FMMVF fibres shall not be classified as toxic to reproduction
according to the criteria in Council Directive 67/548/EEC and Regulation
(EC) 1272/2008.
Effects on developmental toxicity
Description of key information
No effects on fertility or adverse effects to the development of offspring were observed in the OECD 421 screening test on read-across target AES fibres.
Additional information
FMMVF fibres are inorganic fibres of very low biological activity. FMMVF fibres do not translocate after intake (ingestion or inhalation). Due to these characteristics it is evaluated that exposure of the dams will not result in exposure of foetuses.It is assessed that human exposure to FMMVF fibres will not affect the development of human offspring. Consequently, a developmental toxicity study is waived because it is scientifically unjustified.
Justification for classification or non-classification
FMMVF fibres are assessed to possess no toxic properties towards human development and fertility. FMMVF fibres are biosoluble, inorganic fibres of very low biological activity that do not translocate in the body after exposure by inhalation and ingestion. FMMVF fibres shall not be classified as toxic to reproduction according to the criteria in Council Directive 67/548/EEC and Regulation (EC) 1272/2008.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
