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EC number: 232-188-7
CAS number: 7789-75-5
Mean body weights (g) of male and female rats
The acute inhalation toxicity of calcium fluoride was studied by
nose-only exposure of one group of five male and five female rats for a
4 hour period. The test atmosphere contained calcium fluoride dust (MMAD
2.8 um) at the limit concentration of 5.07 g/m3.
After exposure the animals were kept for a 14-day observation period,
then necropsied. Treatment-related effects seen during exposure were
limited to a slightly decreased breathing rate in two animals. No
further abnormalities were detected during after exposure or during the
14 day observation period. A low overall body weight gain was seen in
females. At necropsy, treatment related macroscopic changes were limited
to red/pink discolouration of the lungs in two females. The 4-hour LC50
value of an aerosol of calcium fluoride was found to be greater than
5.07 g/m3 for both sexes under the
conditions of this study.
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