Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 308-516-0 | CAS number: 98072-61-8
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Substance specific information for the UVCB substance "Slimes and Sludges, precious metal refining" is not available for the endpoint “toxicokinetics”. However, there is no specific requirement to generate toxicokinetic data under Regulation (EC) 1907/2006 (REACH). Annex I, Section 1.0.2 of REACH regulation states that “the human health hazard assessment shall consider the toxicokinetic profile (i.e. absorption, metabolism, distribution and elimination) of the substance.” and REACH regulation announces in Annex VIII, Section 8.8.1 that one should perform “assessment of the toxicokinetic behaviour of the substance to the extent that can be derived from the relevant available information”.
Nevertheless, for "Slimes and Sludges, precious metal refining" the human health (HH) hazard assessment is driven by the hazard assessment of the individual UVCB constituents which are (i) classified for HH and (ii) with a content ≥0.1 %. For most of the relevant constituents, toxicokinetic data are fully assessed and included in each individual REACH registration file but were not included in the registration file of "Slimes and Sludges, precious metal refining" (see strategy of registration for UVCB substances – Precious Metals Refinables). Relevant hazard and risk assessment information for Slimes and Sludges, precious metal refining" can be found in Section 7 “Toxicological information_ Slimes and Sludges, precious metal refining”.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
