Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
dermal absorption
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other: QSAR Database
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Guideline:
other: REACH guidance on QSARs R.6, May/July 2008
Principles of method if other than guideline:
Danish (Q)SAR database report

Test material

Constituent 1
Chemical structure
Reference substance name:
2-ethylhexyl palmitate
EC Number:
249-862-1
EC Name:
2-ethylhexyl palmitate
Cas Number:
29806-73-3
Molecular formula:
C24H48O2
IUPAC Name:
2-ethylhexyl palmitate
Details on test material:
- Name of test material (as cited in study report): Hexadecanoic acid, 2-ethylhexyl ester

Results and discussion

Absorption in different matrices:
Dermal absorption of 2-ethylhexyl palmitate was predicted to be 0.00001 mg/cm2/event (very low).

Applicant's summary and conclusion