Registration Dossier
Registration Dossier
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EC number: 931-687-3 | CAS number: -
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
Based on the information provided in the Roquette Safety Data Sheet for Glucidex IT 33 W (dried glucose syrup) and calculated based on the information provided in the Leatherhead Food R.A. Scientific & Technical Surveys, it is scientifically reasonable to expect the solubility to be > 10000 mg/L. Based on this information, it is also scientifically reasonable to predict that the n-octanol/water partition coefficient (log Kow) will be less than -2. Thus, according to section 1 of REACh (Regulation (EC) No 1907/2006) Annex XI, the n-octanol/water partition coefficient (required in Annex VII section 7.8) does not need to be conducted.
Key value for chemical safety assessment
- at the temperature of:
- 20 °C
Additional information
There was no information concerning the dissociation constant of wheat glucose syrups having a DE (dextrose equivalent) of at least 20, and a glucose content of less than 80%.
Mazzobre et al. (2005) determined the partition coefficient of D-glucose (CASRN 50-99-7) by a shake-flask method. The amount of sugar in the organic phase was determined by an enzymatic method. The experimental log Pow was determined to be -2.84 ± 0.03 at 5ºC and -2.82 ± 0.04 at 20ºC. Based on this information, it is scientifically reasonable to predict that the partition coefficient of wheat glucose syrup is expected to be less than -2.
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