Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 270-700-0
CAS number: 68476-80-2
Complex combination obtained by steam distillation of mixed vegetable oils followed by condensation of the steam. Contains fatty acids, sterols, aldehydes and ketones.
study was conducted to determine the dermal penetration potential of the constituent
alpha-tocopherol using three human abdominal skin samples and three
Skh:HR-1 mouse dorsal skin samples. The
skin samples were mounted in Franz-type diffusion cells, with 0.785 cm2
skin surface area exposed. The average cumulative penetration
through human skin for the
was 14 and 227 µg/cm2 after 2 and 24 h respectively. Using mouse skin,
the average cumulative penetration of the
was 50 and 628 µg/cm2 after 2 and 24 h, respectively. Under
the study conditions, penetration of the
mouse skin was approximately three times greater than that through human
skin (Fiume, 2002).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again