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Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
other: reliability not verifiable
Rationale for reliability incl. deficiencies:
other: no detailed information in SNIF#001-4.1.30-01

Data source

Reference
Reference Type:
other: No information provided
Title:
Unnamed
Year:
1987

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 402 (Acute Dermal Toxicity)
GLP compliance:
yes
Limit test:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat
Strain:
Wistar
Sex:
male/female

Administration / exposure

Type of coverage:
occlusive
Vehicle:
polyethylene glycol
Remarks:
400
Doses:
2000 mg/kg bw
No. of animals per sex per dose:
5 males
5 females
Control animals:
not specified

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Based on:
test mat.
Clinical signs:
The treated skin was redly coloured after treatment.
No toxic symptoms could be observed.
Gross pathology:
No substance related damage in organs was found during the postmortem examination.

Any other information on results incl. tables

sex

 dose (mg/kg bw)  numbers of animals  number of deaths
 M  2000  5  0
 F  2000  5  0

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Not subject to classification and labelling.